Sox9 function in craniofacial development and disease.
Ontology highlight
ABSTRACT:
SUBMITTER: Lee YH
PROVIDER: S-EPMC3079054 | biostudies-literature | 2011 Apr
REPOSITORIES: biostudies-literature
Publications
Sox9 function in craniofacial development and disease.
Lee Young-Hoon YH Saint-Jeannet Jean-Pierre JP
Genesis (New York, N.Y. : 2000) 20110401 4
The Sox family of transcriptional regulators has been implicated in the control of a broad array of developmental processes. One member of this family SOX9 was first identified as a candidate gene for campomelic dysplasia (CD), a human syndrome affecting skeletal, and testis development. In these patients most endochondral bones of the face fail to develop resulting in multiple defects such as micrognathia, cleft palate, and facial dysmorphia. In this review we describe Sox9 expression during em ...[more]
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