Developmental expression mapping of a gene implicated in multiple neurodevelopmental disorders, A2bp1 (Fox1).
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ABSTRACT:
SUBMITTER: Hammock EA
PROVIDER: S-EPMC3080782 | biostudies-literature | 2011
REPOSITORIES: biostudies-literature
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Developmental expression mapping of a gene implicated in multiple neurodevelopmental disorders, A2bp1 (Fox1).
Hammock Elizabeth A D EA Levitt Pat P
Developmental neuroscience 20110223 1
The neuronal transcription splicing factor, A2BP1, has been implicated in a variety of neurodevelopmental disorders; however, the role of A2BP1 in brain development and gene regulatory function remains to be explicated. Here, we map A2bp1 gene expression, focusing on the developing forebrain of the C57BL6J mouse. Early in forebrain development, A2bp1 expression is highly reminiscent of the expression of genes marking postmitotic GABAergic cells emanating from the ventral telencephalon during mig ...[more]
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