Ontology highlight
ABSTRACT:
SUBMITTER: Lee YW
PROVIDER: S-EPMC3081620 | biostudies-literature | 2011 Mar
REPOSITORIES: biostudies-literature
Lee Yun-Woo YW Chung Yunju Y Juhn Steven K SK Kim Youngki Y Lin Jizhen J
The Annals of otology, rhinology, and laryngology 20110301 3
<h4>Objectives</h4>Granulation tissue is common in otitis media (OM), yet little is known about the signaling pathways in the formation of granulation tissue in response to infections. In this study, we sought to investigate the activation of the transforming growth factor beta (TGF-beta) signaling pathway in the formation of granulation tissue in response to middle ear pathogens.<h4>Methods</h4>Rat OM models were made by inoculating pneumococcus type 6A or nontypeable Haemophilus influenzae int ...[more]