Ontology highlight
ABSTRACT:
SUBMITTER: Maurer MJ
PROVIDER: S-EPMC3082979 | biostudies-literature | 2011 Apr
REPOSITORIES: biostudies-literature
Maurer Matthew J MJ Micallef Ivana N M IN Cerhan James R JR Katzmann Jerry A JA Link Brian K BK Colgan Joseph P JP Habermann Thomas M TM Inwards David J DJ Markovic Svetomir N SN Ansell Stephen M SM Porrata Luis F LF Johnston Patrick B PB Nowakowski Grzegorz S GS Thompson Carrie A CA Gupta Mamta M Syrbu Sergei I SI Kurtin Paul J PJ Macon William R WR Nikcevich Daniel A DA Witzig Thomas E TE
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20110307 12
<h4>Purpose</h4>The serum free light chain (FLC) assay quantitates free kappa (κ) and free lambda (λ) immunoglobulin light chains. This assay has prognostic value in plasma cell proliferative disorders. There are limited data on serum FLC in B-cell malignancies.<h4>Patients and methods</h4>The association of pretreatment FLC with event-free survival (EFS) and overall survival (OS) in diffuse large B-cell lymphoma (DLBCL) was evaluated in 76 patients from the North Central Cancer Treatment Group ...[more]