Ontology highlight
ABSTRACT:
SUBMITTER: Chao DL
PROVIDER: S-EPMC3084143 | biostudies-literature | 2011 Apr
REPOSITORIES: biostudies-literature
Chao Dennis L DL Halloran M Elizabeth ME Longini Ira M IM
Proceedings of the National Academy of Sciences of the United States of America 20110411 17
In October 2010, a virulent South Asian strain of El Tor cholera began to spread in Haiti. Interventions have included treatment of cases and improved sanitation. Use of cholera vaccines would likely have further reduced morbidity and mortality, but such vaccines are in short supply and little is known about effective vaccination strategies for epidemic cholera. We use a mathematical cholera transmission model to assess different vaccination strategies. With limited vaccine quantities, concentra ...[more]