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Blood vessel deformations on microsecond time scales by ultrasonic cavitation.

ABSTRACT: Transient interactions among ultrasound, microbubbles, and microvessels were studied using high-speed photomicrography. We observed liquid jets, vessel distention (motion outward against the surrounding tissue), and vessel invagination (motion inward toward the lumen). Contrary to current paradigms, liquid jets were directed away from the nearest vessel wall and invagination exceeded distention. These observations provide insight into the mechanics of bubble-vessel interactions, which appear to depend qualitatively upon the mechanical properties of biological tissues.

SUBMITTER: Chen H

PROVIDER: S-EPMC3087441 | biostudies-literature | 2011 Jan

REPOSITORIES: biostudies-literature

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Blood vessel deformations on microsecond time scales by ultrasonic cavitation.

Chen Hong H Kreider Wayne W Brayman Andrew A AA Bailey Michael R MR Matula Thomas J TJ

Physical review letters 20110118 3

Transient interactions among ultrasound, microbubbles, and microvessels were studied using high-speed photomicrography. We observed liquid jets, vessel distention (motion outward against the surrounding tissue), and vessel invagination (motion inward toward the lumen). Contrary to current paradigms, liquid jets were directed away from the nearest vessel wall and invagination exceeded distention. These observations provide insight into the mechanics of bubble-vessel interactions, which appear to ...[more]

PMID: 21405276

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