Ontology highlight
ABSTRACT:
SUBMITTER: Lusebrink J
PROVIDER: S-EPMC3087758 | biostudies-literature | 2011
REPOSITORIES: biostudies-literature
PloS one 20110504 5
Parvoviruses are single stranded DNA viruses that replicate in a so called "rolling-hairpin" mechanism, a variant of the rolling circle replication known for bacteriophages like φX174. The replication intermediates of parvoviruses thus are concatemers of head-to-head or tail-to-tail structure. Surprisingly, in case of the novel human bocavirus, neither head-to-head nor tail-to-tail DNA sequences were detected in clinical isolates; in contrast head-to-tail DNA sequences were identified by PCR and ...[more]