Ontology highlight
ABSTRACT:
SUBMITTER: Hershberger RE
PROVIDER: S-EPMC3088091 | biostudies-literature | 2011 Apr
REPOSITORIES: biostudies-literature
Hershberger Ray E RE Siegfried Jill D JD
Journal of the American College of Cardiology 20110401 16
A great deal of progress has recently been made in the discovery and understanding of the genetics of familial dilated cardiomyopathy (FDC). A consensus has emerged that with a new diagnosis of idiopathic dilated cardiomyopathy (IDC), the clinical screening of first-degree family members will reveal FDC in at least 20% to 35% of those family members. Point mutations in 31 autosomal and 2 X-linked genes representing diverse gene ontogeny have been implicated in causing FDC but account for only 30 ...[more]