Ontology highlight
ABSTRACT:
SUBMITTER: Fermin DR
PROVIDER: S-EPMC3090727 | biostudies-literature | 2008 Dec
REPOSITORIES: biostudies-literature
Fermin David R DR Barac Ana A Lee Sangjin S Polster Sean P SP Hannenhalli Sridhar S Bergemann Tracy L TL Grindle Suzanne S Dyke David B DB Pagani Francis F Miller Leslie W LW Tan Sarah S Dos Remedios Cris C Cappola Thomas P TP Margulies Kenneth B KB Hall Jennifer L JL
Circulation. Cardiovascular genetics 20081209 2
<h4>Background</h4>We report the first comprehensive analysis of gene expression differences by sex and age in left ventricular samples from 102 patients with dilated cardiomyopathy.<h4>Methods and results</h4>Gene expression data (HG-U133A gene chip, Affymetrix) were analyzed from 30 females and 72 males from 3 separate centers. More than 1800 genes displayed sexual dimorphism in the heart (adjusted P value <0.05). A significant number of these genes were highly represented in gene ontology pat ...[more]