Ontology highlight
ABSTRACT:
SUBMITTER: King-Fung Wong T
PROVIDER: S-EPMC3090760 | biostudies-literature | 2011 May
REPOSITORIES: biostudies-literature
King-Fung Wong Thomas T Wing-Yan Cheung Brenda B Lam Tak-Wah TW Yiu Siu-Ming SM
BMC proceedings 20110528
<h4>Background</h4>Predicting new non-coding RNAs (ncRNAs) of a family can be done by aligning the potential candidate with a member of the family with known sequence and secondary structure. Existing tools either only consider the sequence similarity or cannot handle local alignment with gaps.<h4>Results</h4>In this paper, we consider the problem of finding the optimal local structural alignment between a query RNA sequence (with known secondary structure) and a target sequence (with unknown se ...[more]