Ontology highlight
ABSTRACT:
SUBMITTER: Andersson AF
PROVIDER: S-EPMC3091651 | biostudies-literature | 2010
REPOSITORIES: biostudies-literature
Andersson Anders F AF Pelve Erik A EA Lindeberg Stefan S Lundgren Magnus M Nilsson Peter P Bernander Rolf R
BMC genomics 20100728
<h4>Background</h4>Species of the crenarchaeon Sulfolobus harbour three replication origins in their single circular chromosome that are synchronously initiated during replication.<h4>Results</h4>We demonstrate that global gene expression in two Sulfolobus species is highly biased, such that early replicating genome regions are more highly expressed at all three origins. The bias by far exceeds what would be anticipated by gene dosage effects alone. In addition, early replicating regions are den ...[more]