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Electric-Potential Reconstructions of Single Particles Using L-Gradient Flows.

ABSTRACT: In this paper, we present a stable, reliable and robust method for reconstructing a three dimensional density function from a set of two dimensional electron microscopy images. By minimizing an energy functional consisting of a fidelity term and a regularization term, a L(2)-gradient flow is derived. The flow is integrated by a finite element method in the spatial direction and an explicit Euler scheme in temporal direction. The experimental results show that the proposed method is efficient and effective.

SUBMITTER: Li M

PROVIDER: S-EPMC3091820 | biostudies-literature | 2010 Oct

REPOSITORIES: biostudies-literature

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Electric-Potential Reconstructions of Single Particles Using L-Gradient Flows.

Li Ming M Xu Guoliang G Sorzano Carlos O S CO Melero Roberto R Bajaj Chandrajit C

Proceedings of the ... International Conference on Biomedical Engineering and Informatics. International Conference on Biomedical Engineering and Informatics 20101001

In this paper, we present a stable, reliable and robust method for reconstructing a three dimensional density function from a set of two dimensional electron microscopy images. By minimizing an energy functional consisting of a fidelity term and a regularization term, a L(2)-gradient flow is derived. The flow is integrated by a finite element method in the spatial direction and an explicit Euler scheme in temporal direction. The experimental results show that the proposed method is efficient and ...[more]

PMID: 21566727

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