Ontology highlight
ABSTRACT:
SUBMITTER: Rideout EJ
PROVIDER: S-EPMC3092424 | biostudies-literature | 2010 Apr
REPOSITORIES: biostudies-literature
Nature neuroscience 20100321 4
Doublesex proteins, which are part of the structurally and functionally conserved Dmrt gene family, are important for sex determination throughout the animal kingdom. We inserted Gal4 into the doublesex (dsx) locus of Drosophila melanogaster, allowing us to visualize and manipulate cells expressing dsx in various tissues. In the nervous system, we detected differences between the sexes in dsx-positive neuronal numbers, axonal projections and synaptic density. We found that dsx was required for t ...[more]