Ontology highlight
ABSTRACT:
SUBMITTER: Abbas A
PROVIDER: S-EPMC3093414 | biostudies-literature | 2011 Apr
REPOSITORIES: biostudies-literature
Abbas Abdennour A Linman Matthew J MJ Cheng Quan Q
Analytical chemistry 20110321 8
We report a novel optical platform based on SPR generation and confinement inside a defined three-dimensional microwell geometry that leads to background resonance-free SPR images. The array shows an exceptionally high signal-to-noise ratio (S/N > 80) for imaging analysis and subnanometric thickness resolution. An angular sensitivity of 1°/0.01 RIU has been achieved and the signal to background ratio (S/B) improves to 20, 1 order of magnitude higher than that of the best literature results. The ...[more]