Drinking a hot blood meal elicits a protective heat shock response in mosquitoes.
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ABSTRACT:
SUBMITTER: Benoit JB
PROVIDER: S-EPMC3093486 | biostudies-literature | 2011 May
REPOSITORIES: biostudies-literature
Publications
Drinking a hot blood meal elicits a protective heat shock response in mosquitoes.
Benoit Joshua B JB Lopez-Martinez Giancarlo G Patrick Kevin R KR Phillips Zachary P ZP Krause Tyler B TB Denlinger David L DL
Proceedings of the National Academy of Sciences of the United States of America 20110425 19
The mosquito's body temperature increases dramatically when it takes a blood meal from a warm-blooded, vertebrate host. By using the yellow fever mosquito, Aedes aegypti, we demonstrate that this boost in temperature following a blood meal prompts the synthesis of heat shock protein 70 (Hsp70). This response, elicited by the temperature of the blood meal, is most robust in the mosquito's midgut. When RNA interference is used to suppress expression of hsp70, protein digestion of the blood meal is ...[more]
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