Ontology highlight
ABSTRACT:
SUBMITTER: Epstein CB
PROVIDER: S-EPMC30944 | biostudies-literature | 2001 Feb
REPOSITORIES: biostudies-literature
Epstein C B CB Waddle J A JA Hale W W Davé V V Thornton J J Macatee T L TL Garner H R HR Butow R A RA
Molecular biology of the cell 20010201 2
Mitochondrial dysfunction can lead to diverse cellular and organismal responses. We used DNA microarrays to characterize the transcriptional responses to different mitochondrial perturbations in Saccharomyces cerevisiae. We examined respiratory-deficient petite cells and respiratory-competent wild-type cells treated with the inhibitors of oxidative phosphorylation antimycin, carbonyl cyanide m-chlorophenylhydrazone, or oligomycin. We show that respiratory deficiency, but not inhibition of mitoch ...[more]