Ontology highlight
ABSTRACT:
SUBMITTER: Woller B
PROVIDER: S-EPMC3096779 | biostudies-literature | 2011 Jun
REPOSITORIES: biostudies-literature
Biochimica et biophysica acta 20110317 6
RIN proteins serve as guanine nucleotide exchange factors for Rab5a. They are characterized by the presence of a RIN homology domain and a C-terminal Vps9 domain. Currently three family members have been described and analyzed. Here we report the identification of a novel RIN family member, Rin-like (Rinl), that represents a new interaction partner of the receptor tyrosine kinase MuSK, which is an essential key regulator of neuromuscular synapse development. Rinl is localized to neuromuscular sy ...[more]