Ontology highlight
ABSTRACT:
SUBMITTER: Lalier L
PROVIDER: S-EPMC3097003 | biostudies-literature | 2011 Apr
REPOSITORIES: biostudies-literature
Lalier Lisenn L Pedelaborde François F Braud Christophe C Menanteau Jean J Vallette François M FM Olivier Christophe C
BMC cancer 20110427
<h4>Background</h4>NSAIDs exhibit protective properties towards some cancers, especially colon cancer. Yet, it is not clear how they play their protective role. PGE2 is generally shown as the only target of the NSAIDs anticancerous activity. However, PGE2 known targets become more and more manifold, considering both the molecular pathways involved and the target cells in the tumour. The role of PGE2 in tumour progression thus appears complex and multipurpose.<h4>Methods</h4>To gain understanding ...[more]