Paediatric cholestatic liver disease: Diagnosis, assessment of disease progression and mechanisms of fibrogenesis.
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ABSTRACT:
SUBMITTER: Pereira TN
PROVIDER: S-EPMC3097948 | biostudies-literature | 2010 Jun
REPOSITORIES: biostudies-literature
Publications
Paediatric cholestatic liver disease: Diagnosis, assessment of disease progression and mechanisms of fibrogenesis.
Pereira Tamara N TN Pereira Tamara N TN Walsh Meagan J MJ Lewindon Peter J PJ Ramm Grant A GA
World journal of gastrointestinal pathophysiology 20100601 2
Cholestatic liver disease causes significant morbidity and mortality in children. The diagnosis and management of these diseases can be complicated by an inability to detect early stages of fibrosis and a lack of adequate interventional therapy. There is no single gold standard test that accurately reflects the presence of liver disease, or that can be used to monitor fibrosis progression, particularly in conditions such as cystic fibrosis. This has lead to controversy over how suspected liver d ...[more]
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