Ontology highlight
ABSTRACT:
SUBMITTER: Wu Z
PROVIDER: S-EPMC3098101 | biostudies-literature | 2010
REPOSITORIES: biostudies-literature
Wu Zhijin Z Jenkins Bethany D BD Rynearson Tatiana A TA Dyhrman Sonya T ST Saito Mak A MA Mercier Melissa M Whitney Leann P LP
BMC bioinformatics 20101116
<h4>Background</h4>Recent technological advancements have made high throughput sequencing an increasingly popular approach for transcriptome analysis. Advantages of sequencing-based transcriptional profiling over microarrays have been reported, including lower technical variability. However, advances in technology do not remove biological variation between replicates and this variation is often neglected in many analyses.<h4>Results</h4>We propose an empirical Bayes method, titled Analysis of Se ...[more]