Ontology highlight
ABSTRACT:
SUBMITTER: Gratton MA
PROVIDER: S-EPMC3098916 | biostudies-literature | 2011 Jul
REPOSITORIES: biostudies-literature
Gratton Michael Anne MA Eleftheriadou Anna A Garcia Jerel J Verduzco Esteban E Martin Glen K GK Lonsbury-Martin Brenda L BL Vázquez Ana E AE
Hearing research 20101225 1-2
The molecular mechanisms underlying the vast differences between individuals in their susceptibility to noise-induced hearing loss (NIHL) are unknown. The present study demonstrated that the effects of noise over-exposure on the expression of molecules likely to be important in the development of NIHL differ among inbred mouse strains having distinct susceptibilities to NIHL including B6 (B6.CAST) and 129 (129X1/SvJ and 129S1/SvImJ) mice. The noise-exposure protocol produced a loss of 40 dB in h ...[more]