Influenza virus aerosol exposure and analytical system for ferrets.
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ABSTRACT:
SUBMITTER: Gustin KM
PROVIDER: S-EPMC3100970 | biostudies-literature | 2011 May
REPOSITORIES: biostudies-literature
Publications
Influenza virus aerosol exposure and analytical system for ferrets.
Gustin Kortney M KM Belser Jessica A JA Wadford Debra A DA Pearce Melissa B MB Katz Jacqueline M JM Tumpey Terrence M TM Maines Taronna R TR
Proceedings of the National Academy of Sciences of the United States of America 20110502 20
Understanding the transmission ability of newly emerging influenza viruses is central to the development of public health preparedness and prevention strategies. Animals are used to model influenza virus infection and transmission, but the routinely used intranasal inoculation of a liquid virus suspension does not reflect natural infection. We report the development of an inoculation method that delivers an influenza virus aerosol inoculum to ferrets and the characterization of size distribution ...[more]
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