Ontology highlight
ABSTRACT:
SUBMITTER: Dyce PW
PROVIDER: S-EPMC3101249 | biostudies-literature | 2011
REPOSITORIES: biostudies-literature
Dyce Paul W PW Liu Jinghe J Tayade Chandrakant C Kidder Gerald M GM Betts Dean H DH Li Julang J
PloS one 20110524 5
We previously reported that fetal porcine skin-derived stem cells were capable of differentiation into oocyte-like cells (OLCs). Here we report that newborn mice skin-derived stem cells are also capable of differentiating into early OLCs. Using stem cells from mice that are transgenic for Oct4 germline distal enhancer-GFP, germ cells resulting from their differentiation are expected to be GFP(+). After differentiation, some GFP(+) OLCs reached 40-45 µM and expressed oocyte markers. Flow cytometr ...[more]