Ontology highlight
ABSTRACT:
SUBMITTER: Guo S
PROVIDER: S-EPMC3101286 | biostudies-literature | 2011 May
REPOSITORIES: biostudies-literature
Journal of controlled release : official journal of the Controlled Release Society 20110122 3
Because of its large surface area and easy access for both delivery and monitoring, the skin is an attractive target for gene therapy for cutaneous diseases, vaccinations and several metabolic disorders. The critical factors for DNA delivery to the skin by electroporation (EP) are effective expression levels and minimal or no tissue damage. Here, we evaluated the non-invasive multielectrode array (MEA) for gene electrotransfer. For these studies we utilized a guinea pig model, which has been sho ...[more]