Ontology highlight
ABSTRACT:
SUBMITTER: Wu J
PROVIDER: S-EPMC3101833 | biostudies-literature | 2011 Apr
REPOSITORIES: biostudies-literature
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 20110401 2
Traumatic spinal cord injury (SCI) evokes a complex cascade of events with initial mechanical damage leading to secondary injury processes that contribute to further tissue loss and functional impairment. Growing evidence suggests that the cell cycle is activated following SCI. Up-regulation of cell cycle proteins after injury appears to contribute not only to apoptotic cell death of postmitotic cells, including neurons and oligodendrocytes, but also to post-traumatic gliosis and microglial acti ...[more]