Ontology highlight
ABSTRACT:
SUBMITTER: Jha AR
PROVIDER: S-EPMC3102101 | biostudies-literature | 2011
REPOSITORIES: biostudies-literature
Jha Aashish R AR Nixon Douglas F DF Rosenberg Michael G MG Martin Jeffrey N JN Deeks Steven G SG Hudson Richard R RR Garrison Keith E KE Pillai Satish K SK
PloS one 20110525 5
HERV-K113 and HERV-K115 have been considered to be among the youngest HERVs because they are the only known full-length proviruses that are insertionally polymorphic and maintain the open reading frames of their coding genes. However, recent data suggest that HERV-K113 is at least 800,000 years old, and HERV-K115 even older. A systematic study of HERV-K HML2 members to identify HERVs that may have infected the human genome in the more recent evolutionary past is lacking. Therefore, we sought to ...[more]