Ontology highlight
ABSTRACT:
SUBMITTER: Kluza E
PROVIDER: S-EPMC3102848 | biostudies-literature | 2011 May
REPOSITORIES: biostudies-literature
Kluza Ewelina E Heisen Marieke M Schmid Sophie S van der Schaft Daisy W J DW Schiffelers Raymond M RM Storm Gert G ter Haar Romeny Bart M BM Strijkers Gustav J GJ Nicolay Klaas K
Angiogenesis 20110112 2
Inflammation plays a prominent role in tumor growth. Anti-inflammatory drugs have therefore been proposed as anti-cancer therapeutics. In this study, we determined the anti-angiogenic activity of a single dose of liposomal prednisolone phosphate (PLP-L), by monitoring tumor vascular function and viability over a period of one week. C57BL/6 mice were inoculated subcutaneously with B16F10 melanoma cells. Six animals were PLP-L-treated and six served as control. Tumor tissue and vascular function w ...[more]