Ontology highlight
ABSTRACT:
SUBMITTER: Ahmady E
PROVIDER: S-EPMC3103349 | biostudies-literature | 2011 Jun
REPOSITORIES: biostudies-literature
Ahmady Elmira E Deeke Shelley A SA Rabaa Seham S Kouri Lara L Kenney Laura L Stewart Alexandre F R AF Burgon Patrick G PG
The Journal of biological chemistry 20110415 22
Mutations in the A-type lamin (LMNA) gene are associated with age-associated degenerative disorders of mesenchymal tissues, such as dilated cardiomyopathy, Emery-Dreifuss muscular dystrophy, and limb-girdle muscular dystrophy. The molecular mechanisms that connect mutations in LMNA with different human diseases are poorly understood. Here, we report the identification of a Muscle-enriched A-type Lamin-interacting Protein, MLIP (C6orf142 and 2310046A06rik), a unique single copy gene that is an in ...[more]