BrainAligner: 3D registration atlases of Drosophila brains.
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ABSTRACT:
SUBMITTER: Peng H
PROVIDER: S-EPMC3104101 | biostudies-literature | 2011 Jun
REPOSITORIES: biostudies-literature
Publications
BrainAligner: 3D registration atlases of Drosophila brains.
Peng Hanchuan H Chung Phuong P Long Fuhui F Qu Lei L Jenett Arnim A Seeds Andrew M AM Myers Eugene W EW Simpson Julie H JH
Nature methods 20110501 6
Analyzing Drosophila melanogaster neural expression patterns in thousands of three-dimensional image stacks of individual brains requires registering them into a canonical framework based on a fiducial reference of neuropil morphology. Given a target brain labeled with predefined landmarks, the BrainAligner program automatically finds the corresponding landmarks in a subject brain and maps it to the coordinate system of the target brain via a deformable warp. Using a neuropil marker (the antibod ...[more]
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