Ontology highlight
ABSTRACT:
SUBMITTER: Fahed AC
PROVIDER: S-EPMC3104361 | biostudies-literature | 2011 Apr
REPOSITORIES: biostudies-literature
Fahed Akl C AC Nemer Georges M GM
Nutrition & metabolism 20110422 1
Familial Hypercholesterolemia (FH) is a common cause of premature cardiovascular disease and is often undiagnosed in young people. Although the disease is diagnosed clinically by high LDL cholesterol levels and family history, to date there are no single internationally accepted criteria for the diagnosis of FH. Several genes have been shown to be involved in FH; yet determining the implications of the different mutations on the phenotype remains a hard task. The polygenetic nature of FH is bein ...[more]