Differential RNA-binding activity of the hnRNP G protein correlated with the sex genotype in the amphibian oocyte.
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ABSTRACT:
SUBMITTER: Kanhoush R
PROVIDER: S-EPMC3105392 | biostudies-literature | 2011 May
REPOSITORIES: biostudies-literature
Publications
Differential RNA-binding activity of the hnRNP G protein correlated with the sex genotype in the amphibian oocyte.
Kanhoush Rasha R Praseuth Danièle D Perrin Caroline C Chardard Dominique D Vinh Joëlle J Penrad-Mobayed May M
Nucleic acids research 20110129 10
A proteomic approach has enabled the identification of an orthologue of the splicing factor hnRNP G in the amphibians Xenopus tropicalis, Ambystoma mexicanum, Notophthalmus viridescens and Pleurodeles walt, which shows a specific RNA-binding affinity similar to that of the human hnRN G protein. Three isoforms of this protein with a differential binding affinity for a specific RNA probe were identified in the P. walt oocyte. In situ hybridization to lampbrush chromosomes of P. waltl revealed the ...[more]
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