Dataset Information
Signaling gateway molecule pages--a data model perspective.
Ontology highlight
ABSTRACT: Summary
The Signaling Gateway Molecule Pages (SGMP) database provides highly structured data on proteins which exist in different functional states participating in signal transduction pathways. A molecule page starts with astate of a native protein, without any modification and/or interactions. New states are formed with every post-translational modification or interaction with one or more proteins, small molecules or class molecules and with each change in cellular location. State transitions are caused by a combination of one or more modifications, interactions and translocations which then might be associated with one or more biological processes. In a characterized biological state, a molecule can function as one of several entities or their combinations, including channel, receptor, enzyme, transcription factor and transporter. We have also exported SGMP data to the Biological Pathway Exchange (BioPAX) and Systems Biology Markup Language (SBML) as well as in our custom XML.Availability
SGMP is available at www.signaling-gateway.org/molecule.
SUBMITTER: Dinasarapu AR
PROVIDER: S-EPMC3106186 | biostudies-literature | 2011 Jun
REPOSITORIES: biostudies-literature
Publications
Signaling gateway molecule pages--a data model perspective.
Bioinformatics (Oxford, England) 20110419 12
<h4>Summary</h4>The Signaling Gateway Molecule Pages (SGMP) database provides highly structured data on proteins which exist in different functional states participating in signal transduction pathways. A molecule page starts with astate of a native protein, without any modification and/or interactions. New states are formed with every post-translational modification or interaction with one or more proteins, small molecules or class molecules and with each change in cellular location. State tran ...[more]