Ontology highlight
ABSTRACT:
SUBMITTER: Staykova M
PROVIDER: S-EPMC3107321 | biostudies-literature | 2011 May
REPOSITORIES: biostudies-literature
Staykova Margarita M Holmes Douglas P DP Read Clarke C Stone Howard A HA
Proceedings of the National Academy of Sciences of the United States of America 20110511 22
Cells are wrapped in inelastic membranes, yet they can sustain large mechanical strains by regulating their area. The area regulation in cells is achieved either by membrane folding or by membrane exo- and endocytosis. These processes involve complex morphological transformations of the cell membrane, i.e., invagination, vesicle fusion, and fission, whose precise mechanisms are still under debate. Here we provide mechanistic insights into the area regulation of cell membranes, based on the previ ...[more]