Ontology highlight
ABSTRACT:
SUBMITTER: McKie JM
PROVIDER: S-EPMC310757 | biostudies-literature | 1998 Aug
REPOSITORIES: biostudies-literature
McKie J M JM Wadey R B RB Sutherland H F HF Taylor C L CL Scambler P J PJ
Genome research 19980801 8
We have used a modified direct selection technique to detect transcripts that are both evolutionary conserved and developmentally expressed. The enrichment for homologous mouse cDNAs by use of human genomic DNA as template is shown to be an efficient and rapid approach for generating transcript maps. Deletions of human 22q11 are associated with several clinical syndromes, with overlapping phenotypes, for example, velocardiofacial syndrome (VCFS) and DiGeorge syndrome (DGS). A large number of tra ...[more]