Ontology highlight
ABSTRACT:
SUBMITTER: Landreville S
PROVIDER: S-EPMC3107995 | biostudies-literature | 2011
REPOSITORIES: biostudies-literature
Landreville Solange S Lupien Caroline B CB Vigneault Francois F Gaudreault Manon M Mathieu Mélissa M Rousseau Alain P AP Guérin Sylvain L SL Salesse Christian C
Molecular vision 20110513
<h4>Purpose</h4>Uveal melanoma (UM) is the most common primary cancer of the eye, resulting not only in vision loss, but also in metastatic death. This study attempts to identify changes in the patterns of gene expression that lead to malignant transformation and proliferation of normal uveal melanocytes (UVM) using the Suppressive Subtractive Hybridization (SSH) technique.<h4>Methods</h4>The SSH technique was used to isolate genes that are differentially expressed in the TP31 cell line derived ...[more]