Ontology highlight
ABSTRACT:
SUBMITTER: Tang SC
PROVIDER: S-EPMC3108368 | biostudies-literature | 2010 Dec
REPOSITORIES: biostudies-literature
Tang Sydney C W SC Leung Violet T M VT Chan Loretta Y Y LY Wong Sunny S H SS Chu Daniel W S DW Leung Joseph C K JC Ho Yiu Wing YW Lai Kar Neng KN Ma Lijun L Elbein Steven C SC Bowden Donald W DW Hicks Pamela J PJ Comeau Mary E ME Langefeld Carl D CD Freedman Barry I BI
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20100602 12
<h4>Background</h4>A single-nucleotide polymorphism (SNP), rs2268388, in the acetyl-coenzyme A carboxylase beta (ACACB) gene is associated with susceptibility to type 2 diabetic nephropathy (T2DN) in Japanese and European-American populations. Whether this association also exists in Chinese patients is unclear. Attempts at replication in small Singaporean and Korean samples were not significant.<h4>Methods</h4>Eight ACACB SNPs were genotyped in 595 subjects with type 2 diabetes mellitus born in ...[more]