Ontology highlight
ABSTRACT:
SUBMITTER: Mutti DO
PROVIDER: S-EPMC3109057 | biostudies-literature | 2011 Jun
REPOSITORIES: biostudies-literature
Mutti Donald O DO Cooper Margaret E ME Dragan Ecaterina E Jones-Jordan Lisa A LA Bailey Melissa D MD Marazita Mary L ML Murray Jeffrey C JC Zadnik Karla K
Investigative ophthalmology & visual science 20110601 6
<h4>Purpose</h4>Epidemiologic evidence indicates that time outdoors reduces the risk of myopia, suggesting a possible role for vitamin D. This case-control study was conducted to determine whether single-nucleotide polymorphisms (SNPs) within VDR at 12q13.11 and GC at 4q12-13 are associated with myopia.<h4>Methods</h4>The primary analysis was conducted on 81 white adult control subjects between 18 and 50 years of age with a spherical equivalent refractive error between +0.50 and +2.00 D in both ...[more]