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Human vocal cord infection with the Microsporidium Anncaliia algerae.

ABSTRACT: We describe a biopsy proven case of microsporidial infection of the false vocal cords in a 69-yr-old male with a history of chronic lymphocytic leukemia. The patient had hoarseness for several weeks before his admission to the hospital for shortness of breath. He had received chemotherapy with fludarabine 6 wk before this hospital admission. A biopsy of vocal cord nodules demonstrated an organism that was identified as Anncaliia algerae by electron microscopy. Molecular analysis of the small subunit RNA gene amplified by polymerase chain reaction further confirmed the identification of this organism as A. algerae. This case illustrates the ability of this insect pathogen to cause disease in immune-compromised mammalian hosts.

SUBMITTER: Cali A

PROVIDER: S-EPMC3109663 | biostudies-literature | 2010 Nov-Dec

REPOSITORIES: biostudies-literature

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Human vocal cord infection with the Microsporidium Anncaliia algerae.

Cali Ann A Neafie Ronald R Weiss Louis M LM Ghosh Kaya K Vergara Rebecca B RB Gupta Rachna R Takvorian Peter M PM

The Journal of eukaryotic microbiology 20101019 6

We describe a biopsy proven case of microsporidial infection of the false vocal cords in a 69-yr-old male with a history of chronic lymphocytic leukemia. The patient had hoarseness for several weeks before his admission to the hospital for shortness of breath. He had received chemotherapy with fludarabine 6 wk before this hospital admission. A biopsy of vocal cord nodules demonstrated an organism that was identified as Anncaliia algerae by electron microscopy. Molecular analysis of the small sub ...[more]

PMID: 20958855

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