Ontology highlight
ABSTRACT:
SUBMITTER: Pinto N
PROVIDER: S-EPMC3110519 | biostudies-literature | 2011 Jun
REPOSITORIES: biostudies-literature
Pinto Navin N Dolan M Eileen ME
Current drug metabolism 20110601 5
In the field of pharmacogenetics, we currently have a few markers to guide physicians as to the best course of therapy for patients. For the most part, these genetic variants are within a drug metabolizing enzyme that has a large effect on the degree or rate at which a drug is converted to its metabolites. For many drugs, response and toxicity are multi-genic traits and understanding relationships between a patient's genetic variation in drug metabolizing enzymes and the efficacy and/or toxicity ...[more]