Ontology highlight
ABSTRACT:
SUBMITTER: Ferru E
PROVIDER: S-EPMC3112043 | biostudies-literature | 2011 Jun
REPOSITORIES: biostudies-literature
Ferru Emanuela E Giger Katie K Pantaleo Antonella A Campanella Estela E Grey Jesse J Ritchie Ken K Vono Rosa R Turrini Francesco F Low Philip S PS
Blood 20110407 22
The cytoplasmic domain of band 3 serves as a center of erythrocyte membrane organization and constitutes the major substrate of erythrocyte tyrosine kinases. Tyrosine phosphorylation of band 3 is induced by several physiologic stimuli, including malaria parasite invasion, cell shrinkage, normal cell aging, and oxidant stress (thalassemias, sickle cell disease, glucose-6-phosphate dehydrogenase deficiency, etc). In an effort to characterize the biologic sequelae of band 3 tyrosine phosphorylation ...[more]