Ontology highlight
ABSTRACT:
SUBMITTER: Chamberlain BT
PROVIDER: S-EPMC3112310 | biostudies-literature | 2011 Jun
REPOSITORIES: biostudies-literature
The Journal of organic chemistry 20110525 12
The first examples of α-azido bisphosphonates [(RO)(2)P(O)](2)CXN(3) (1, R = i-Pr, X = Me; 2, R = i-Pr, X = H; 3, R = H, X = Me; 4, R = H, X = H) and corresponding β,γ-CXN(3) dGTP (5-6) and α,β-CXN(3) dATP (7-8) analogues are described. The individual diastereomers of 7 (7a/b) were obtained by HPLC separation of the dADP synthetic precursor (14a/b). ...[more]