Ontology highlight
ABSTRACT:
SUBMITTER: Reddy SS
PROVIDER: S-EPMC3113299 | biostudies-literature | 2011 May
REPOSITORIES: biostudies-literature
Reddy Sunil S SS Connor Teal E TE Weeber Edwin J EJ Rebeck William W
Molecular neurodegeneration 20110509
Very Low Density Lipoprotein Receptor (VLDLR) and Apolipoprotein E Receptor 2 (ApoER2) are important receptors in the brain for mediating the signaling effects of the extracellular matrix protein Reelin, affecting neuronal function in development and in the adult brain. VLDLR and ApoER2 are members of the low density lipoprotein family, which also mediates the effects of numerous other extracellular ligands, including apolipoprotein E. Although VLDLR and ApoER2 are highly homologous, they differ ...[more]