Ontology highlight
ABSTRACT:
SUBMITTER: Mineur YS
PROVIDER: S-EPMC3113664 | biostudies-literature | 2011 Jun
REPOSITORIES: biostudies-literature
Science (New York, N.Y.) 20110601 6035
Smoking decreases appetite, and smokers often report that they smoke to control their weight. Understanding the neurobiological mechanisms underlying the anorexic effects of smoking would facilitate the development of novel treatments to help with smoking cessation and to prevent or treat obesity. By using a combination of pharmacological, molecular genetic, electrophysiological, and feeding studies, we found that activation of hypothalamic α3β4 nicotinic acetylcholine receptors leads to activat ...[more]