Ontology highlight
ABSTRACT:
SUBMITTER: Ye Y
PROVIDER: S-EPMC3113943 | biostudies-literature | 2011 May
REPOSITORIES: biostudies-literature
Ye Yuzhen Y Choi Jeong-Hyeon JH Tang Haixu H
BMC bioinformatics 20110515
<h4>Background</h4>Next Generation Sequencing (NGS) is producing enormous corpuses of short DNA reads, affecting emerging fields like metagenomics. Protein similarity search--a key step to achieve annotation of protein-coding genes in these short reads, and identification of their biological functions--faces daunting challenges because of the very sizes of the short read datasets.<h4>Results</h4>We developed a fast protein similarity search tool RAPSearch that utilizes a reduced amino acid alpha ...[more]