Ontology highlight
ABSTRACT:
SUBMITTER: Bretscher AJ
PROVIDER: S-EPMC3115024 | biostudies-literature | 2011 Mar
REPOSITORIES: biostudies-literature
Bretscher Andrew Jonathan AJ Kodama-Namba Eiji E Busch Karl Emanuel KE Murphy Robin Joseph RJ Soltesz Zoltan Z Laurent Patrick P de Bono Mario M
Neuron 20110301 6
Homeostatic control of body fluid CO(2) is essential in animals but is poorly understood. C. elegans relies on diffusion for gas exchange and avoids environments with elevated CO(2). We show that C. elegans temperature, O(2), and salt-sensing neurons are also CO(2) sensors mediating CO(2) avoidance. AFD thermosensors respond to increasing CO(2) by a fall and then rise in Ca(2+) and show a Ca(2+) spike when CO(2) decreases. BAG O(2) sensors and ASE salt sensors are both activated by CO(2) and rem ...[more]