Anoxia- and hypoxia-induced expression of LDH-A* in the Amazon Oscar, Astronotus crassipinis.
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ABSTRACT:
SUBMITTER: Almeida-Val VM
PROVIDER: S-EPMC3115329 | biostudies-literature | 2011 Apr
REPOSITORIES: biostudies-literature
Publications
Anoxia- and hypoxia-induced expression of LDH-A* in the Amazon Oscar, Astronotus crassipinis.
Almeida-Val Vera Maria Fonseca VM Oliveira Alice Reis AR de Nazaré Paula da Silva Maria M Ferreira-Nozawa Monica Stropa MS Araújo Roziete Mendes RM Val Adalberto Luis AL Nozawa Sérgio Ricardo SR
Genetics and molecular biology 20110401 2
Adaptation or acclimation to hypoxia occurs via the modulation of physiologically relevant genes, such as erythropoietin, transferrin, vascular endothelial growth factor, phosphofructokinase and lactate dehydrogenase A. In the present study, we have cloned, sequenced and examined the modulation of the LDH-A gene after an Amazonian fish species, Astronotus crassipinis (the Oscar), was exposed to hypoxia and anoxia. In earlier studies, we have discovered that adults of this species are extremely t ...[more]
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