Ontology highlight
ABSTRACT:
SUBMITTER: Desrosiers DC
PROVIDER: S-EPMC3115443 | biostudies-literature | 2011 Jun
REPOSITORIES: biostudies-literature
Desrosiers Daniel C DC Anand Arvind A Luthra Amit A Dunham-Ems Star M SM LeDoyt Morgan M Cummings Michael A D MA Eshghi Azad A Cameron Caroline E CE Cruz Adriana R AR Salazar Juan C JC Caimano Melissa J MJ Radolf Justin D JD
Molecular microbiology 20110427 6
Definitive identification of Treponema pallidum rare outer membrane proteins (OMPs) has long eluded researchers. TP0326, the sole protein in T. pallidum with sequence homology to a Gram-negative OMP, belongs to the BamA family of proteins essential for OM biogenesis. Structural modelling predicted that five polypeptide transport-associated (POTRA) domains comprise the N-terminus of TP0326, while the C-terminus forms an 18-stranded amphipathic β-barrel. Circular dichroism, heat modifiability by S ...[more]