Ontology highlight
ABSTRACT:
SUBMITTER: Yan X
PROVIDER: S-EPMC3116110 | biostudies-literature | 2011 Jul
REPOSITORIES: biostudies-literature
Inflammatory bowel diseases 20101128 7
<h4>Background</h4>Both maternal obesity and inflammatory bowel diseases (IBDs) are increasing. It was hypothesized that maternal obesity induces an inflammatory response in the fetal large intestine, predisposing offspring to IBDs.<h4>Methods</h4>Nonpregnant ewes were assigned to a control (Con, 100% of National Research Council [NRC] recommendations) or obesogenic (OB, 150% of NRC) diet from 60 days before conception. The large intestine was sampled from fetuses at 135 days (term 150 days) aft ...[more]