Ontology highlight
ABSTRACT:
SUBMITTER: Ruhnow F
PROVIDER: S-EPMC3117161 | biostudies-literature | 2011 Jun
REPOSITORIES: biostudies-literature
Ruhnow Felix F Zwicker David D Diez Stefan S
Biophysical journal 20110601 11
Recent developments in image processing have greatly advanced our understanding of biomolecular processes in vitro and in vivo. In particular, using Gaussian models to fit the intensity profiles of nanometer-sized objects have enabled their two-dimensional localization with a precision in the one-nanometer range. Here, we present an algorithm to precisely localize curved filaments whose structures are characterized by subresolution diameters and micrometer lengths. Using surface-immobilized micr ...[more]