Ontology highlight
ABSTRACT:
SUBMITTER: Crack JC
PROVIDER: S-EPMC3117330 | biostudies-literature | 2011 Feb
REPOSITORIES: biostudies-literature
Crack Jason C JC Smith Laura J LJ Stapleton Melanie R MR Peck Jamie J Watmough Nicholas J NJ Buttner Mark J MJ Buxton Roger S RS Green Jeffrey J Oganesyan Vasily S VS Thomson Andrew J AJ Le Brun Nick E NE
Journal of the American Chemical Society 20101223 4
The reactivity of protein bound iron-sulfur clusters with nitric oxide (NO) is well documented, but little is known about the actual mechanism of cluster nitrosylation. Here, we report studies of members of the Wbl family of [4Fe-4S] containing proteins, which play key roles in regulating developmental processes in actinomycetes, including Streptomyces and Mycobacteria, and have been shown to be NO responsive. Streptomyces coelicolor WhiD and Mycobacterium tuberculosis WhiB1 react extremely rapi ...[more]